ÇAĞDAŞ İSLAM TARİHİ YAZARLARININ 9. YÜZYILDAKİ ZENCİ İSYANINA TEPKİLERİ (M.S. 869-883)
نویسندگان
چکیده
منابع مشابه
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The technology of flap prefabrications is a new, powerful tool in plastic and reconstructive surgery. It is based on an old idea, while applying the latest innovations in surgery. It involves any modification of a surgical flap done before its transfer to the final donor site, including surgical delay, pre-expansion, pre-grafting, the use of tissue engineering, biomaterials and perforators surg...
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It is important to examine the cytochrome P450 2C19 (CYP2C19) genetic contribution to drug disposition and responses of CYP2C19 substrates during drug development. Design of such clinical trials requires projection of genotype-dependent in vivo clearance and associated variabilities of the investigational drug, which is not generally available during early stages of drug development, but is ess...
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Data from the clinical absolute bioavailability (F) study with cobimetinib suggested that F was lower than predicted based on its low hepatic extraction and good absorption. The CYP3A4 transgenic (Tg) mouse model with differential expression of CYP3A4 in the liver (Cyp3aTg-3A4Hep) or intestine (Cyp3a Tg-3A4Int) and both liver and intestine (Cyp3aTg-3A4Hep/Int) were used to study the contributio...
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Phenethylisothiocyanate (PEITC), a naturally occurring isothiocyanate and potent cancer chemopreventive agent, works by multiple mechanisms, including the inhibition of cytochrome P450 (P450) enzymes, such as CYP2E1, that are involved in the bioactivation of carcinogens. PEITC has been reported to be a mechanismbased inactivator of some P450s. We describe here the possible mechanism for the ina...
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ژورنال
عنوان ژورنال: Journal of International Social Research
سال: 2020
ISSN: 1307-9581
DOI: 10.17719/jisr.11322